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Effects of PEEP on regional ventilation-perfusion mismatch in the acute respiratory distress syndrome


ABSTRACT:

Purpose

In the acute respiratory distress syndrome (ARDS), decreasing Ventilation-Perfusion

Methods

In fifteen patients with moderate and severe ARDS, two PEEP levels (5 and 15 cmH2O) were applied in random order.

Results

In the non-dependent region, at higher PEEP, ventilation reaching the normal

Conclusions

In patients with ARDS, higher PEEP optimizes the distribution of both ventilation (in the non-dependent areas) and perfusion (in the middle and dependent lung). Bedside measure of recruitability is associated with improved

Supplementary Information

The online version contains supplementary material available at 10.1186/s13054-022-04085-y.

SUBMITTER: Pavlovsky B 

PROVIDER: S-EPMC9272883 | biostudies-literature |

REPOSITORIES: biostudies-literature

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