Association of Lesion Location and Fatigue Symptoms After Ischemic Stroke: A VLSM Study.

ABSTRACT:

Background

Poststroke fatigue (PSF) is a common symptom in stroke survivors, yet its anatomical mechanism is unclear. Our study was aimed to identify which brain lesions are related to the PSF in patients with acute stroke.

Method

Patients with first-ever acute ischemic stroke consecutively admitted from the first affiliated hospital of the University of Science and Technology of China (USTC) between January 2017 and June 2020. Fatigue was scored using the Fatigue Severity Scale. All the participants were assessed by 3.0 T brain MRI including diffusion-weighted imaging. The infarct lesions were delineated manually and transformed into a standard template. Voxel-based lesion-symptom mapping (VLSM) was applied to investigate the association between lesion location and the occu

SUBMITTER: Wang J 

PROVIDER: S-EPMC9277067 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature