Ontology highlight
ABSTRACT:
SUBMITTER: Xin R
PROVIDER: S-EPMC9277212 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Xin Rui R Tang Xiao-Mei XM Jiang Ying-Jie YJ Yu Fei F Li Sha S Jia Cheng-You CY Wang Gao-Ren GR Fu Da D Fu Da D Liu Ji-Bin JB Ma Yu-Shui YS
Journal of oncology 20220705
Colorectal cancer (CRC) includes colon adenocarcinoma (COAD) and rectal adenocarcinoma (READ). Competitive endogenous RNA (ceRNA) is crucial for cancer pathogenesis. Abnormal expression of MYC is generally associated with a poor colon adenocarcinoma prognosis. The present study aimed to identify a novel MYC-associated ceRNA regulatory network and identify potential prognostic markers associated with COAD. We obtained the transcriptome sequencing profiles of 462 COAD cases from the TCGA database ...[more]