Ontology highlight
ABSTRACT:
SUBMITTER: Carlin AF
PROVIDER: S-EPMC9278181 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Carlin Aaron F AF Clark Alex E AE Chaillon Antoine A Garretson Aaron F AF Bray William W Porrachia Magali M Santos AsherLev T AT Rana Tariq M TM Smith Davey M DM
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20230201 3
We isolated a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.2 variant from a person with coronavirus disease 2019 recrudescence after nirmatrelvir/ritonavir treatment. Antiviral sensitivity and neutralizing antibody testing were performed with both parental SARS-CoV-2 and multiple variants of concern. We found that neither nirmatrelvir resistance nor absence of neutralizing immunity was a likely cause of the recrudescence. ...[more]