Dataset Information

Healthy cities initiative in China: Progress, challenges, and the way forward.

ABSTRACT: China implemented the first phase of its National Healthy Cities pilot program from 2016-20. Along with related urban health governmental initiatives, the program has helped put health on the agenda of local governments while raising public awareness. Healthy City actions taken at the municipal scale also prepared cities to deal with the COVID-19 pandemic. However, after intermittent trials spanning the past two decades, the Healthy Cities initiative in China has reached a crucial juncture. It risks becoming inconsequential given its overlap with other health promotion efforts, changing public health priorities in response to the pandemic, and the partial adoption of the Healthy Cities approach advanced by the World Health Organization (WHO). We recommend aligning the Healthy Cities initiative in China with strategic national and global level agendas such as Healthy China 2030 and the Sustainable Development Goals (SDGs) by providing an integrative governance framework to facilitate a coherent intersectoral program to systemically improve population health. Achieving this alignment will require leveraging the full spectrum of best practices in Healthy Cities actions and expanding assessment efforts.

Funding

Tsinghua-Toyota Joint Research Fund "Healthy city systems for smart cities" program.

SUBMITTER: Bai Y

PROVIDER: S-EPMC9286727 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Publications

Healthy cities initiative in China: Progress, challenges, and the way forward.

Bai Yuqi Y Zhang Yutong Y Zotova Olena O Pineo Helen H Siri José J Liang Lu L Luo Xiangyu X Kwan Mei-Po MP Ji John J Jiang Xiaopeng X Chu Cordia C Cong Na N Lin Vivian V Summerskill William W Luo Yong Y Yu Hongjun H Wu Tinghai T Yang Changhong C Li Jing J Xiao Yixiong Y Zhou Jingbo J Dou Dejing D Xiong Hui H Zhang Lee Ligang LL Wang Lan L Tao Shu S Fu Bojie B Zhang Yong Y Xu Bing B Yang Jun J Gong Peng P

The Lancet regional health. Western Pacific 20220715

China implemented the first phase of its National Healthy Cities pilot program from 2016-20. Along with related urban health governmental initiatives, the program has helped put health on the agenda of local governments while raising public awareness. Healthy City actions taken at the municipal scale also prepared cities to deal with the COVID-19 pandemic. However, after intermittent trials spanning the past two decades, the Healthy Cities initiative in China has reached a crucial juncture. It r ...[more]

PMID: 35854811

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Project description:BackgroundWhole genome sequence data is a step towards generating the 'parts list' of life to understand the underlying principles of Biocomplexity. Genome sequencing initiatives of human and model organisms are targeted efforts towards understanding principles of evolution with an application envisaged to improve human health. These efforts culminated in the development of dedicated resources. Whereas a large number of viral genomes have been sequenced by groups or individuals with an interest to study antigenic variation amongst strains and species. These independent efforts enabled viruses to attain the status of 'best-represented taxa' with the highest number of genomes. However, due to lack of concerted efforts, viral genomic sequences merely remained as entries in the public repositories until recently.ResultsVirGen is a curated resource of viral genomes and their analyses. Since its first release, it has grown both in terms of coverage of viral families and development of new modules for annotation and analysis. The current release (2.0) includes data for twenty-five families with broad host range as against eight in the first release. The taxonomic description of viruses in VirGen is in accordance with the ICTV nomenclature. A well-characterised strain is identified as a 'representative entry' for every viral species. This non-redundant dataset is used for subsequent annotation and analyses using sequenced-based Bioinformatics approaches. VirGen archives precomputed data on genome and proteome comparisons. A new data module that provides structures of viral proteins available in PDB has been incorporated recently. One of the unique features of VirGen is predicted conformational and sequential epitopes of known antigenic proteins using in-house developed algorithms, a step towards reverse vaccinology.ConclusionStructured organization of genomic data facilitates use of data mining tools, which provides opportunities for knowledge discovery. One of the approaches to achieve this goal is to carry out functional annotations using comparative genomics. VirGen, a comprehensive viral genome resource that serves as an annotation and analysis pipeline has been developed for the curation of public domain viral genome data http://bioinfo.ernet.in/virgen/virgen.html. Various steps in the curation and annotation of the genomic data and applications of the value-added derived data are substantiated with case studies.

Dataset Information

Healthy cities initiative in China: Progress, challenges, and the way forward.

Funding

Publications

Healthy cities initiative in China: Progress, challenges, and the way forward.

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