Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC).
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ABSTRACT:
SUBMITTER: Hwang M
PROVIDER: S-EPMC9290135 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
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Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC).
Hwang Mina M Kim Hyo-Sup HS Jin Sang-Man SM Hur Kyu Yeon KY Kim Jae-Hyeon JH Lee Moon-Kyu MK
Journal of cellular physiology 20210616 12
Thiazolidinediones are synthetic PPARγ ligands that enhance insulin sensitivity, and that could increase insulin secretion from β-cells. However, the functional role and mechanism(s) of action in pancreatic β-cells have not been investigated in detail. ...[more]
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