Metabolic dysfunction-associated fatty liver disease improves detection of high liver stiffness: The Rotterdam Study.

ABSTRACT:

Background and aims

Recently metabolic dysfunction-associated fatty liver disease (MAFLD) has been introduced and was defined as hepatic steatosis with either overweight, diabetes, and/or a combination of other metabolic risk factors. We investigated the application of the MAFLD criteria as compared with NAFLD.

Approach and results

We performed a cross-sectional analysis within the Rotterdam Study, a large prospective population-based cohort. Participants who attended the liver ultrasound and transient elastography program between 2009 and 2014 were eligible for inclusion. Subsequently, individuals with viral hepatitis, alcohol intake >60 g/day, missing alcohol data, and/or missing body mass index were excluded. According to their NAFLD and MAFLD status based on metadata and

SUBMITTER: van Kleef LA 

PROVIDER: S-EPMC9299928 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature