Ontology highlight
ABSTRACT:
SUBMITTER: Hong B
PROVIDER: S-EPMC9300463 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Hong Benke B Grzech Dagny D Caputi Lorenzo L Sonawane Prashant P López Carlos E Rodríguez CER Kamileen Mohamed Omar MO Hernández Lozada Néstor J NJ Grabe Veit V O'Connor Sarah E SE
Nature 20220706 7919
Strychnine is a natural product that, through isolation, structural elucidation and synthetic efforts, shaped the field of organic chemistry. Currently, strychnine is used as a pesticide to control rodents<sup>1</sup> because of its potent neurotoxicity<sup>2,3</sup>. The polycyclic architecture of strychnine has inspired chemists to develop new synthetic transformations and strategies to access this molecular scaffold<sup>4</sup>, yet it is still unknown how plants create this complex structure ...[more]