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ABSTRACT: Supplementary information
The online version contains supplementary material available at 10.1007/s10068-022-01079-y.
SUBMITTER: Lim T
PROVIDER: S-EPMC9300784 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Lim Taehwan T Lee Kiuk K Kim Ryun Hee RH Cha Kwang Hyun KH Koo Song Yi SY Moon Eun Chae EC Hwang Keum Taek KT
Food science and biotechnology 20220410 8
Blood trimethylamine-N-oxide (TMAO) has been associated with cardiovascular disease. Black raspberry (<i>Rubus occidentalis</i>, BR) has been regarded to be beneficial for cardiovascular health. This study aimed to investigate how BR extract affects serum lipid profile, gut microbial composition, metabolites in rats fed TMAO with a high-fat diet. Dietary TMAO increased serum LDL cholesterol, while BR extract decreased its level. α-Diversity of gut microbiota was not changed; however, in the rats ...[more]