Estimation of Early Graft Function Using the BETA-2 Score Following Clinical Islet Transplantation.

ABSTRACT: Little is known about how early islet graft function evolves in the clinical setting. The BETA-2 score is a validated index of islet function that can be calculated from a single blood sample and lends itself to frequent monitoring of graft function. In this study, we characterized early graft function by calculating weekly BETA-2 score in recipients who achieved insulin independence after single transplant (group 1, n = 8) compared to recipients who required a second transplant before achieving insulin independence (group 2, n = 7). We also determined whether graft function 1-week post-transplant was associated with insulin independence in individuals who received initial transplant between 2000-2017 (n = 125). Our results show that graft function increased rapidly re

SUBMITTER: Lam A 

PROVIDER: S-EPMC9301872 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature