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Innovative approach for first-trimester fetal organ volume measurements using a Virtual Reality system: The Generation R Next Study.


ABSTRACT:

Introduction

To investigate the reproducibility of first-trimester fetal organ volume measurements using three-dimensional (3D) ultrasound and a Virtual Reality system.

Methods

Within a population-based prospective cohort study, 3D ultrasound datasets of 25 first-trimester fetuses were collected by three sonographers. We used the V-scope application to perform Virtual Reality volume assessments of the fetal heart, lungs, and kidneys. All measurements were performed by two independent researchers.

Results

Intraobserver analyses for volume measurements of the fetal heart, lungs, and kidneys showed intraclass correlation coefficients ≥0.86, mean differences ≤8.3%, and coefficients of variation ≤22.8%. Interobserver analyses showed sufficient agreement for right lung volume measurements, but consistent measurement differences between observers for left lung, heart, and kidney volume measurements (p-values <0.05).

Conclusion

We observed sufficient intraobserver reproducibility, but overall suboptimal interobserver reproducibility for first-trimester fetal heart, lung, and kidney volume measurements using an innovative Virtual Reality approach. In the current stage, these measurements might be promising for the use in research settings. The reproducibility of the measurements might be further improved by novel post-processing algorithms.

SUBMITTER: Wiertsema CJ 

PROVIDER: S-EPMC9306822 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature

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Publications

Innovative approach for first-trimester fetal organ volume measurements using a Virtual Reality system: The Generation R Next Study.

Wiertsema Clarissa J CJ   Sol Chalana M CM   Mulders Annemarie G M G J AGMGJ   Steegers Eric A P EAP   Duijts Liesbeth L   Gaillard Romy R   Koning Anton H J AHJ   Jaddoe Vincent W V VWV  

The journal of obstetrics and gynaecology research 20220129 3


<h4>Introduction</h4>To investigate the reproducibility of first-trimester fetal organ volume measurements using three-dimensional (3D) ultrasound and a Virtual Reality system.<h4>Methods</h4>Within a population-based prospective cohort study, 3D ultrasound datasets of 25 first-trimester fetuses were collected by three sonographers. We used the V-scope application to perform Virtual Reality volume assessments of the fetal heart, lungs, and kidneys. All measurements were performed by two independ  ...[more]

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