Antibiotic resistance in Salmonella enterica serovar Typhimurium exposed to microcin-producing Escherichia coli.
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ABSTRACT:
SUBMITTER: Carlson SA
PROVIDER: S-EPMC93088 | biostudies-literature | 2001 Aug
REPOSITORIES: biostudies-literature
Publications
Antibiotic resistance in Salmonella enterica serovar Typhimurium exposed to microcin-producing Escherichia coli.
Carlson S A SA Frana T S TS Griffith R W RW
Applied and environmental microbiology 20010801 8
Microcin 24 is an antimicrobial peptide secreted by uropathogenic Escherichia coli. Secretion of microcin 24 provides an antibacterial defense mechanism for E. coli. In a plasmid-based system using transformed Salmonella enterica, we found that resistance to microcin 24 could be seen in concert with a multiple-antibiotic resistance phenotype. This multidrug-resistant phenotype appeared when Salmonella was exposed to an E. coli strain expressing microcin 24. Therefore, it appears that multidrug-r ...[more]
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