4D-printed bilayer hydrogel with adjustable bending degree for enteroatmospheric fistula closure.

ABSTRACT: Recently, four-dimensional (4D) shape-morphing structures, which can dynamically change shape over time, have attracted much attention in biomedical manufacturing. The 4D printing has the capacity to fabricate dynamic construction conforming to the natural bending of biological tissues, superior to other manufacturing techniques. In this study, we presented a multi-responsive, flexible, and biocompatible 4D-printed bilayer hydrogel based on acrylamide-acrylic acid/cellulose nanocrystal (AAm-AAc/CNC) network. The first layer was first stretched and then formed reversible coordination with Fe³⁺ to maintain this pre-stretched length; it was later combined with a second layer. The deformation process was actuated by the reduction of Fe³⁺ to Fe²⁺ in the first la

SUBMITTER: Qu G 

PROVIDER: S-EPMC9309522 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature