Dataset Information

The role of keratinized mucosa width as a risk factor for peri-implant disease: A systematic review, meta-analysis, and trial sequential analysis.

ABSTRACT:

Background

Studies have examined the benefit of having keratinized peri-implant mucosa width with mixed results.

Purpose

This study examines whether the lack of a prespecified (2 mm) amount of keratinized mucosa width (KMW) is a risk factor for peri-implant diseases.

Methods

A systematic electronic and manual search of randomized or nonrandomized controlled or noncontrolled clinical trials was conducted. Qualitative review, quantitative meta-analysis, and trial sequence analysis (TSA) of implants inserted at sites with <2 mm or ≥2 mm of KMW were analyzed to compare all the predetermined outcome variables. The level of evidence concerning the role of KMW in peri-implant health was evaluated via the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system guide.

Results

Nine studies were included in the qualitative analysis and four in the meta-analysis and TSA. No significant inter-group difference (p > 0.05) and a low power of evidence were found for probing depth, soft-tissue recession, and marginal bone loss. A significant difference favoring ≥2 mm KMW had a lower mean plaque index (MD = 0.37, 95% CI: [0.16, 0.58], p = 0.002) (3 studies, 430 implants, low-quality evidence). GRADE system showed very low and low quality of evidence for all other outcome measures.

Conclusion

Based on the available studies, the impact of amount of KMW (either <2 mm or ≥ 2 mm) as a risk factor for developing peri-implant disease remains low. Future control studies with proper sample size and longer follow-up are needed to further validate current findings.

SUBMITTER: Ravida A

PROVIDER: S-EPMC9311272 | biostudies-literature |

REPOSITORIES: biostudies-literature

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