Review of Antimicrobial Resistance in Wastewater in Japan: Current Challenges and Future Perspectives.

ABSTRACT: Antimicrobial resistance (AMR) circulates through humans, animals, and the environments, requiring a One Health approach. Recently, urban sewage has increasingly been suggested as a hotspot for AMR even in high-income countries (HICs), where the water sanitation and hygiene infrastructure are well-developed. To understand the current status of AMR in wastewater in a HIC, we reviewed the epidemiological studies on AMR in the sewage environment in Japan from the published literature. Our review showed that a wide variety of clinically important antibiotic-resistant bacteria (ARB), antibiotic resistance genes (ARGs), and antimicrobial residues are present in human wastewater in Japan. Their concentrations are lower than in low- and middle-income countries (LMICs) and are further reduced by se

SUBMITTER: Baba H 

PROVIDER: S-EPMC9312076 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature