Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC9312471 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Wang Shiwei S Lin Haoyu H Huang Zhixian Z He Yufeng Y Deng Xiaobing X Xu Youjun Y Pei Jianfeng J Lai Luhua L
Biomolecules 20220711 7
Location and properties of ligand binding sites provide important information to uncover protein functions and to direct structure-based drug design approaches. However, as binding site detection depends on the three-dimensional (3D) structural data of proteins, functional analysis based on protein ligand binding sites is formidable for proteins without structural information. Recent developments in protein structure prediction and the 3D structures built by AlphaFold provide an unprecedented op ...[more]