Standardised uptake values as determined on prostate-specific membrane antigen positron emission tomography/computed tomography is associated with oncological outcomes in patients with prostate cancer.

ABSTRACT:

Objectives

To investigate the association between intraprostatic, intratumoral maximum standardised uptake values (SUV_max ) on prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) in patients with prostate cancer (PCa) prior to robot-assisted radical prostatectomy (RARP) and pathology outcomes, including pathological International Society of Urological Pathology score (pISUP) and lymph node (LN) status (pN0/pN1).

Patients and methods

A bi-centric, secondary analysis of two previous, prospective cohort studies was performed in 318 patients with biopsy confirmed PCa and who were scheduled for RARP. Before surgery, patients received a PSMA PET/CT with either ⁶⁸ Ga-PSMA-11 (59% of the patients) or ¹⁸

SUBMITTER: Bodar YJL 

PROVIDER: S-EPMC9315142 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature