Contrasting Diversity and Composition of Human Colostrum Microbiota in a Maternal Cohort With Different Ethnic Origins but Shared Physical Geography (Island Scale).

ABSTRACT: Colostrum represents an important source for the transfer of important commensal bacteria from mother to newborn and has a strong impact on the newborn's health after birth. However, the composition of the colostrum microbiome is highly heterogeneous due to geographic factors and ethnicity (maternal, cultural, and subsistence factors). By analyzing the colostrum 16S rRNA gene full-length sequencing dataset in 97 healthy mothers (60 from Han, 37 from Li) from the Hainan island of China, we showed that the ethnic differences of the colostrum microbiome in a maternal cohort with different ethnic origins shared physical geography. Results indicated that the richness of microbial community in colostrum of Han women was higher than that of Li women, but there was no significant difference in Sha

SUBMITTER: Xie W 

PROVIDER: S-EPMC9315263 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature