Antiparasitic Drugs against SARS-CoV-2: A Comprehensive Literature Survey.

ABSTRACT: More than two years have passed since the viral outbreak that led to the novel infectious respiratory disease COVID-19, caused by the SARS-CoV-2 coronavirus. Since then, the urgency for effective treatments resulted in unprecedented efforts to develop new vaccines and to accelerate the drug discovery pipeline, mainly through the repurposing of well-known compounds with broad antiviral effects. In particular, antiparasitic drugs historically used against human infections due to protozoa or helminth parasites have entered the main stage as a miracle cure in the fight against SARS-CoV-2. Despite having demonstrated promising anti-SARS-CoV-2 activities in vitro, conflicting results have made their translation into clinical practice more difficult than expected. Since many studies involving ant

SUBMITTER: Calvo-Alvarez E 

PROVIDER: S-EPMC9320270 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature