Ontology highlight
ABSTRACT:
SUBMITTER: Yadav P
PROVIDER: S-EPMC9324244 | biostudies-literature | 2022 Jun
REPOSITORIES: biostudies-literature
Yadav Pardeep P El-Kafrawy Sherif A SA El-Day Mai M MM Alghafari Wejdan T WT Faizo Arwa A AA Jha Saurabh Kumar SK Dwivedi Vivek Dhar VD Azhar Esam I EI
Life (Basel, Switzerland) 20220624 7
The Japanese encephalitis virus (JEV), a mosquito-borne flavivirus that causes viral encephalitis leading to neural damage, is a major threat in most Asian countries. The RNA-dependent RNA polymerase (RdRp) present in the viral genome is the key component for genome replication, making it an attractive target for antiviral drug development. In this study, the natural products from <i>Echinacea angustifolia</i> were retrieved for structure-based virtual screening against JEV-RdRp. The top six com ...[more]