Ontology highlight
ABSTRACT:
SUBMITTER: De Paolis V
PROVIDER: S-EPMC9324337 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
De Paolis Veronica V Maiullari Fabio F Chirivì Maila M Milan Marika M Cordiglieri Chiara C Pagano Francesca F La Manna Alessandra Rita AR De Falco Elena E Bearzi Claudia C Rizzi Roberto R Parisi Chiara C
International journal of molecular sciences 20220718 14
The cellular heterogeneity of the tumor environment of breast cancer (BC) is extremely complex and includes different actors such as neoplastic, stromal, and immunosuppressive cells, which contribute to the chemical and mechanical modification of the environment surrounding the tumor-exasperating immune-escaping mechanisms. In addition to molecular signals that make the tumor microenvironment (TME) unacceptable for the penetrance of the immune system, the physical properties of tumoral extracell ...[more]