Ontology highlight
ABSTRACT:
SUBMITTER: Nkone P
PROVIDER: S-EPMC9324365 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Nkone Paballo P Loubser Shayne S Quinn Thomas C TC Redd Andrew D AD Laeyendecker Oliver O Tiemessen Caroline T CT Mayaphi Simnikiwe H SH
Viruses 20220721 7
HIV-1 incidence is an important parameter for assessing the impact of HIV-1 interventions. The aim of this study was to evaluate HIV-1 polymerase (pol) gene sequence diversity for the prediction of recent HIV-1 infections. Complete pol Sanger sequences obtained from 45 participants confirmed to have recent or chronic HIV-1 infection were used. Shannon entropy was calculated for amino acid (aa) sequences for the entire pol and for sliding windows consisting of 50 aa each. Entropy scores for the c ...[more]