Dataset Information

Types of diet, obesity, and incident type 2 diabetes: Findings from the UK Biobank prospective cohort study.

ABSTRACT:

Aim

To investigate the associations between types of diet and incident type 2 diabetes and whether adiposity mediated these associations.

Materials and methods

In total, 203 790 participants from UK Biobank (mean age 55.2 years; 55.8% women) without diabetes at baseline were included in this prospective study. Using the dietary intake data self-reported at baseline, participants were categorized as vegetarians (n = 3237), fish eaters (n = 4405), fish and poultry eaters (n = 2217), meat eaters (n = 178 004) and varied diet (n = 15 927). The association between type of diet and incident type 2 diabetes was investigated using Cox-proportional hazards models with a 2-year landmark analysis. The mediation role of adiposity was tested under a counterfactual framework.

Results

After excluding the first 2 years of follow-up, the median follow-up was 5.4 (IQR: 4.8-6.3) years, during which 5067 (2.5%) participants were diagnosed with type 2 diabetes. After adjusting for lifestyle factors, fish eaters (HR 0.52 [95% CI: 0.39-0.69]) and fish and poultry eaters (HR 0.62 [95% CI: 0.45-0.88]) had a lower risk of incident type 2 diabetes compared with meat eaters. The association for vegetarians was not significant. Varied diet had a higher risk of type 2 diabetes. Obesity partially mediated the association of fish (30.6%), fish and poultry (49.8%) and varied (55.2%) diets.

Conclusions

Fish eaters, as well as fish and poultry eaters, were at a lower risk of incident type 2 diabetes than meat eaters, partially attributable to lower obesity risk.

SUBMITTER: Boonpor J

PROVIDER: S-EPMC9325356 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Publications

Types of diet, obesity, and incident type 2 diabetes: Findings from the UK Biobank prospective cohort study.

Boonpor Jirapitcha J Petermann-Rocha Fanny F Parra-Soto Solange S Pell Jill P JP Gray Stuart R SR Celis-Morales Carlos C Ho Frederick K FK

Diabetes, obesity & metabolism 20220425 7

<h4>Aim</h4>To investigate the associations between types of diet and incident type 2 diabetes and whether adiposity mediated these associations.<h4>Materials and methods</h4>In total, 203 790 participants from UK Biobank (mean age 55.2 years; 55.8% women) without diabetes at baseline were included in this prospective study. Using the dietary intake data self-reported at baseline, participants were categorized as vegetarians (n = 3237), fish eaters (n = 4405), fish and poultry eaters (n = 2217), ...[more]

PMID: 35373896

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Dataset Information

Types of diet, obesity, and incident type 2 diabetes: Findings from the UK Biobank prospective cohort study.

Aim

Materials and methods

Results

Conclusions

Publications

Types of diet, obesity, and incident type 2 diabetes: Findings from the UK Biobank prospective cohort study.

Similar Datasets

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