ABSTRACT: Highlights • Statistical analysis using physicochemical parameters reveals that the processes involved in the hot springs of HGB may include water mixing or exhibiting simple dissolution, ion exchange and reverse ion exchange.• Study shows the water in the hot springs of HGB is mainly Na-Cl, Na-HCO3, Ca+2-Na+-HCO3−, Ca+2- HCO3− and mixed type.• Geothermometry reveals the temperature of these geothermal features ranges approximately between 100-250°C.• Microbial study reveals that the Proteobacteria, Firmicutes, Bacteroidetes and Actinobacteria as predominant phyla showing significant positive correlation with physicochemical parameters like temperature, pH, Na, HCO3, etc. Extreme ecosystems with enormous arrays of physicochemical or biological physiognomies serve as an important indicator of various processes occurred and/or occurring in and on the Earth. Among extreme habitats, hot springs represent geothermal features which are complex systems with a well-defined plumbing system. Besides geological tectonic based hypsography and orology annotations, the hot springs have served as hot spots for ages where there is an amalgamation of nature, religion, faith, health, and science. Thus, there remains an escalating scope to study these hot springs all over the world. The Himalayan Geothermal Belt (HGB) banquets three densely demographic countries i.e. Pakistan, India and China, that hosts numerous hot springs. Studies on the hot springs distributed over these countries reveal Proteobacteria, Firmicutes, Bacteroidetes and Actinobacteria as the predominant bacterial phyla. The bacterial diversity shows a significant positive correlation with physicochemical parameters like temperature, pH, Na+, HCO3−, etc. Physicochemical analyses of these hot springs indicate the water mainly as Na-Cl, Na-HCO3, SO4-Cl, and mixed type, with temperature ranging approximately between 100-250°C as predicted by various geothermometers. Numerous studies although done, not much of a comprehensive database of the analysis are provided on the hot springs harboured by the HGB. This review aims to give a cumulative illustration on comparative facets of various characteristic features of hot springs distributed over the HGB. These are found to be of great importance with respect to the exploitation of geothermal energy and microflora in various sectors of industries and biotechnology. They are also important sources in terms of socio-economic perspective, and routes to eco-medical tourism. Graphical Abstract Image, graphical abstract
