Dataset Information

The Pentacam® AXL Wave provides a reliable wavefront-based objective refraction when compared to manifest subjective refraction: A prospective study.

ABSTRACT:

Purpose

Accurate refraction is arguably the most important parameter for a successful laser vision correction surgery and is based on a combination of manifest and cycloplegic refraction. Wavefront-based objective refraction may be useful in the evaluation of patients. So far, the reliability of objective refraction as measured using the Pentacam^® AXL Wave has not been published in the literature.

Methods

This was a prospective study including a total of 168 eyes belonging to 84 young non-presbyopic patients evaluated for refractive surgery. Pentacam^® AXL Wave full sequence was taken for all patients. Then, a clinician who was unaware of the objective refraction results performed a full physical examination, including manifest refraction starting from an autorefractometer value. All refraction values were transferred to astigmatic power vectors as per the Thibos method. Reliability of the different vectors and a unifying blur value were compared using Spearman correlation, Bland-Altman plot, and intraclass correlation coefficient.

Results

The mean age was 28.8 ± 5.4 years, with a female preponderance (60.7%). The correlation between both eyes was high. The difference in M vector between subjective and objective refraction was 0.16 D, while the difference was 0.04 and 0.01 D for the J₀ and J₄₅ vectors, respectively. Paired samples Student t was non-significant for all comparisons. Spearman rho correlations were high (0.666-0.924, all P < 0.001). Intraclass correlation coefficients were also high (0.890-0.966). Bland-Altman plots did not demonstrate any systematic errors.

Conclusion

Wavefront-based refractive refraction obtained using the Pentacam^® AXL Wave is highly agreeable and correlated with measurements obtained by manifest subjective refraction.

SUBMITTER: Balparda K

PROVIDER: S-EPMC9332961 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

The Pentacam® AXL Wave provides a reliable wavefront-based objective refraction when compared to manifest subjective refraction: A prospective study.

Balparda Kepa K Acevedo-Urrego Andrea A Silva-Quintero Laura Andrea LA Herrera-Chalarca Tatiana T

Indian journal of ophthalmology 20220501 5

<h4>Purpose</h4>Accurate refraction is arguably the most important parameter for a successful laser vision correction surgery and is based on a combination of manifest and cycloplegic refraction. Wavefront-based objective refraction may be useful in the evaluation of patients. So far, the reliability of objective refraction as measured using the Pentacam<sup>®</sup> AXL Wave has not been published in the literature.<h4>Methods</h4>This was a prospective study including a total of 168 eyes belong ...[more]

PMID: 35502018

Similar Datasets

Project description:BackgroundPatient adherence to treatment is key to preventing the worsening of neurological disability in multiple sclerosis (MS). The RebiSmart® autoinjector facilitates self-administration of subcutaneous interferon β-1a (sc IFN β-1a) and records objective adherence data. The CORE study was undertaken to evaluate the relationship between subjectively reported and objective adherence of MS patients using RebiSmart® in Switzerland and explore variables associated with objective adherence.MethodsPatients with relapsing-remitting MS who were treated with sc IFN β-1a 44 or 22 μg three times weekly using RebiSmart® for at least 9 months participated in this phase IV non-interventional study. Neurologist questionnaires were used at month 0 to collect patient demographics, medical history and estimates of patients' adherence. Patient questionnaires were used to record subjective patient-reported adherence at month 0 and estimates of variables influencing adherence. Objective adherence data were obtained from the RebiSmart® log-files at months 0 and 6.ResultsOf 56 patients who completed the observation period, 53 had evaluable data. Objective adherence differed significantly between self-reported compliant (n = 33) and non-compliant groups (n = 20) (p = 0.00001). Older age, greater disability, patient's perception of the importance of ease of use and storage, being well informed about RebiSmart® features and neurologists' estimations of adherence were all positively associated with treatment adherence.ConclusionsWe showed for the first time that subjective patient-reported adherence in MS was well in line with objective adherence, suggesting that the frequency of administration is reported accurately by patients to their neurologist. This observation may have implications for future treatment monitoring strategies and strategic medical decisions. Patients, particularly those who are younger and with lower levels of disability, may benefit from being better informed of the importance of being adherent to their treatments and receiving information about their medication and the device they are using.

Dataset Information

The Pentacam® AXL Wave provides a reliable wavefront-based objective refraction when compared to manifest subjective refraction: A prospective study.

Purpose

Methods

Results

Conclusion

Publications

The Pentacam® AXL Wave provides a reliable wavefront-based objective refraction when compared to manifest subjective refraction: A prospective study.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets