Ontology highlight
ABSTRACT:
SUBMITTER: Geissdorfer W
PROVIDER: S-EPMC93931 | biostudies-literature | 1999 Jul
REPOSITORIES: biostudies-literature
Geissdörfer W W Kok R G RG Ratajczak A A Hellingwerf K J KJ Hillen W W
Journal of bacteriology 19990701 14
Alkanes are oxidized in Acinetobacter sp. strain ADP1 by a three-component alkane monooxygenase, composed of alkane hydroxylase, rubredoxin, and rubredoxin reductase. rubA and rubB encode rubredoxin and a NAD(P)H-dependent rubredoxin reductase. We demonstrate here that single base pair substitutions in rubA or rubB lead to defects in alkane degradation, showing that both genes are essential for alkane utilization. Differences in the degradation capacity for hexadecane and dodecane in these mutan ...[more]