Saliva microbiome, dietary, and genetic markers are associated with suicidal ideation in university students.
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ABSTRACT:
SUBMITTER: Ahrens AP
PROVIDER: S-EPMC9395396 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
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Saliva microbiome, dietary, and genetic markers are associated with suicidal ideation in university students.
Ahrens Angelica P AP Sanchez-Padilla Diego E DE Drew Jennifer C JC Oli Monika W MW Roesch Luiz F W LFW Triplett Eric W EW
Scientific reports 20220822 1
Here, salivary microbiota and major histocompatibility complex (MHC) human leukocyte antigen (HLA) alleles were compared between 47 (12.6%) young adults with recent suicidal ideation (SI) and 325 (87.4%) controls without recent SI. Several bacterial taxa were correlated with SI after controlling for sleep issues, diet, and genetics. Four MHC class II alleles were protective for SI including DRB1*04, which was absent in every subject with SI while present in 21.7% of controls. Increased incidence ...[more]
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2024-03-06 | GSE247998 | GEO