Ontology highlight
ABSTRACT:
SUBMITTER: Siedow A
PROVIDER: S-EPMC93980 | biostudies-literature | 1999 Aug
REPOSITORIES: biostudies-literature
Siedow A A Cramm R R Siddiqui R A RA Friedrich B B
Journal of bacteriology 19990801 16
The conjugative 450-kb megaplasmid pHG1 is essential for the anaerobic growth of Alcaligenes eutrophus H16 in the presence of nitrate as the terminal electron acceptor. We identified two megaplasmid-borne genes (nrdD and nrdG) which are indispensable under these conditions. Sequence alignment identified significant similarity of the 76.2-kDa gene product NrdD and the 30.9-kDa gene product NrdG with anaerobic class III ribonucleotide reductases and their corresponding activases. Deletion of nrdD ...[more]