Molecular basis of the key regulator WRINKLED1 in plant oil biosynthesis.
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ABSTRACT:
SUBMITTER: Qiao Z
PROVIDER: S-EPMC9401623 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Publications
Molecular basis of the key regulator WRINKLED1 in plant oil biosynthesis.
Qiao Zhu Z Kong Que Q Tee Wan Ting WT Lim Audrey R Q ARQ Teo Miao Xuan MX Olieric Vincent V Low Pui Man PM Yang Yuzhou Y Qian Guoliang G Ma Wei W Gao Yong-Gui YG
Science advances 20220824 34
Vegetable oils are not only major components of human diet but also vital for industrial applications. WRINKLED1 (WRI1) is a pivotal transcription factor governing plant oil biosynthesis, but the underlying DNA-binding mechanism remains incompletely understood. Here, we resolved the structure of Arabidopsis WRI1 (AtWRI1) with its cognate double-stranded DNA (dsDNA), revealing two antiparallel β sheets in the tandem AP2 domains that intercalate into the adjacent major grooves of dsDNA to determin ...[more]
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