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[Research progress and application of retention time prediction method based on deep learning].


ABSTRACT:

SUBMITTER: DU Z 

PROVIDER: S-EPMC9403805 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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[Research progress and application of retention time prediction method based on deep learning].

DU Zhuokun Z   Shao Wei W   Qin Weijie W  

Se pu = Chinese journal of chromatography 20210301 3


In "shotgun" proteomics strategy, the proteome is explained by analyzing tryptic digested peptides using liquid chromatography-mass spectrometry. In this strategy, the retention time of peptides in liquid chromatography separation can be predicted based on the peptide sequence. This is a useful feature for peptide identification. Therefore, the prediction of the retention time has attracted much research attention. Traditional methods calculate the physical and chemical properties of the peptide  ...[more]

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