Ontology highlight
ABSTRACT:
SUBMITTER: De Wulf P
PROVIDER: S-EPMC94143 | biostudies-literature | 1999 Nov
REPOSITORIES: biostudies-literature
De Wulf P P Kwon O O Lin E C EC
Journal of bacteriology 19991101 21
In Escherichia coli, the CpxRA two-component signal transduction system senses and responds to aggregated and misfolded proteins in the bacterial envelope. We show that CpxR-P (the phosphorylated form of the cognate response regulator) activates cpxRA expression in conjunction with RpoS, suggesting an involvement of the Cpx system in stationary-phase survival. Engagement of the CpxRA system in functions beyond protein management is indicated by several putative targets identified after a genomic ...[more]