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Social capital as a network measure provides new insights on economic growth.

ABSTRACT: Unveiling the main drivers of economic growth is of paramount importance. Previous research recognizes the critical role played by the factors of production: capital and labor. However, the exact mechanisms that underpin Total Factor Productivity (TFP) are not fully understood. An increasing number of studies suggests that the creation and transmission of knowledge, factor supply and economic integration are indeed crucial. Yet, the need for a systematic and unifying framework still exists. Nowadays capital and labor are embedded into a complex network structure through global supply chains and international migration. Recent research has established a link between network centralities and different types of social capital. In this work we employ the OECD's Multi-Regional Input-Output and International Migration datasets to build the network representation for capital and labor of 63 economies during 10 years. We then examine the role of social capital measures as drivers of the TFP adopting an extended Cobb-Douglass production function and addressing potential issues such as multicollinearity, reverse causality and non-linear effects. Our results indicate that social capital in the factors of production networks can significantly drive economic outputs through TFP.

SUBMITTER: Oliver Huidobro J

PROVIDER: S-EPMC9417001 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Social capital as a network measure provides new insights on economic growth.

Oliver Huidobro Jaime J Antonioni Alberto A Lipari Francesca F Tamarit Ignacio I

PloS one 20220826 8

Unveiling the main drivers of economic growth is of paramount importance. Previous research recognizes the critical role played by the factors of production: capital and labor. However, the exact mechanisms that underpin Total Factor Productivity (TFP) are not fully understood. An increasing number of studies suggests that the creation and transmission of knowledge, factor supply and economic integration are indeed crucial. Yet, the need for a systematic and unifying framework still exists. Nowa ...[more]

PMID: 36018843

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Project description:RacA is the main Rho GTPase in Aspergillus niger regulating polarity maintenance via controlling actin dynamics. We have previously shown that both deletion and dominant activation of RacA (RacG18V) provoke an actin localization defect and thereby loss of polarized tip extension. This loss of apical dominance results in frequent dichotomous branching in the racA deletion strain and an apolar growing phenotype for RacG18V. In the current study we investigated the transcriptomics and physiological consequences of these morphological changes and compared the data with our previously established morphogenetic network model for the dichotomous branching mutant ramosa-1. This integrated approach revealed that polar tip growth is most likely orchestrated by the concerted activities of phospholipid signaling, sphingolipid signaling, TORC2 signaling, calcium signaling and CWI signaling pathways. The transcriptomic signatures and the reconstructed network model for all three morphology mutants imply that these pathways become integrated to bring about different physiological adaptations including changes in sterol, zinc and amino acid metabolism and changes in ion transport and protein trafficking. We furthermore followed that fate of exocytotic (SncA) and endocytotic (AbpA, SlaB) markers in the dichotomous branching racA deletion mutant, and provide data demonstrating that hyperbranching does not per se result in increased protein secretion. This data set consists of 14 samples in total and covers the genome-wide transcriptional responses of Aspergillus niger towards deletion of racA and expression of a dominant active racA allele (G18V). The genome-wide transcriptional effect of deleting racA was monitored by comparison with the A. niger wild type. For both, the racA deletion mutant and the wild type, samples consist of biological triplicates (6 in total). The genome-wide transcriptional effect of expressing the dominant active racA mutant allele was monitored by sampling 2 and 4 hours after induction with maltose. For comparison, the racA wild type allele was induced and expressed similarly and samples were taken at corresponding time points. The experimental setup for the dominant active racA expression consisted of biological triplicates (8 in total).

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Social capital as a network measure provides new insights on economic growth.

Publications

Social capital as a network measure provides new insights on economic growth.

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