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Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation.

ABSTRACT: Cell-imprinted substrates direct stem cell differentiation into various lineages, suggesting the idea of lineage-specific nanotopography. We herein examined the surface topography of five different imprinted cell patterns using AFM imaging and statistical analysis of amplitude, spatial, and hybrid roughness parameters. The results suggest that different cell imprints possess distinguished nanotopographical features.

SUBMITTER: Kamguyan K

PROVIDER: S-EPMC9419843 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature

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Cell-imprinted substrates: in search of nanotopographical fingerprints that guide stem cell differentiation.

Kamguyan Khorshid K Zajforoushan Moghaddam Saeed S Nazbar Abolfazl A Haramshahi Seyyed Mohammad Amin SMA Taheri Shiva S Bonakdar Shahin S Thormann Esben E

Nanoscale advances 20201208 2

Cell-imprinted substrates direct stem cell differentiation into various lineages, suggesting the idea of lineage-specific nanotopography. We herein examined the surface topography of five different imprinted cell patterns using AFM imaging and statistical analysis of amplitude, spatial, and hybrid roughness parameters. The results suggest that different cell imprints possess distinguished nanotopographical features. ...[more]

PMID: 36131729

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