Promiscuous origin of a chimeric sequence in the Escherichia coli O157:H7 genome.

ABSTRACT: A novel sequence of 2.9 kb in the intergenic region between the mutS and rpoS genes of Escherichia coli O157:H7 and closely related strains replaces a sequence of 6.1 kb in E. coli K-12 strains. At the same locus in Shigella dysenteriae type 1, a sequence identical to that in O157:H7 is bounded by the IS1 insertion sequence element. Extensive polymorphism in the mutS-rpoS chromosomal region is indicative of horizontal transfer events.

SUBMITTER: LeClerc JE 

PROVIDER: S-EPMC94221 | biostudies-literature | 1999 Dec

REPOSITORIES: biostudies-literature