Dataset Information

New insights on growth trajectory in infants with complex congenital heart disease.

ABSTRACT:

Purpose

We aimed to describe the weight-for-age Z-score growth trajectory (WAZ-GT) of infants with complex congenital heart disease (cCHD) after neonatal cardiac surgery in the first 4 months of life and assess potential risk factors.

Methods

We utilized data from a previously reported trial of the REACH telehealth home monitoring (NCT01941667) program which evaluated 178 infants with cCHD from 2012 to 2017. Over the first 4 months of life, weekly infant weights were converted to WAZ. WAZ-GT classes were identified using latent class growth modeling. Multinomial logistic regression models were used to examine the associations between potential risk factors and WAZ-GT classes.

Results

Four distinct classes of WAZ-GT were identified: maintaining WAZ > 0, 14%; stable around WAZ = 0, 35%; partially recovered, 28%; never recovered, 23%. Compared with reference group "stable around WAZ=0," we identified clinical and sociodemographic determinants of class membership for the three remaining groups. "Maintaining WAZ > 0" had greater odds of having biventricular physiology, borderline appetite, and a parent with at least a college education. "Partially recovered" had greater odds of hospital length of stay>14 days and being a single child in the household. "Never recovered" had greater odds hospital length of stay >14 and > 30 days, tube feeding at discharge, and low appetite.

Conclusions

This study described distinct classes of WAZ-GT for infants with cCHD early in infancy and identified associated determinants.

Practice implications

Findings from this study can be used in the identification of infants at risk of poor WAZ-GT and in the design of interventions to target growth in this vulnerable patient population.

SUBMITTER: Lisanti AJ

PROVIDER: S-EPMC9427721 | biostudies-literature | 2022 Sep-Oct

REPOSITORIES: biostudies-literature

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Publications

New insights on growth trajectory in infants with complex congenital heart disease.

Lisanti Amy Jo AJ Min Jungwon J Golfenshtein Nadya N Ravishankar Chitra C Costello John M JM Huang Liming L Fleck Desiree D Medoff-Cooper Barbara B

Journal of pediatric nursing 20220520

<h4>Purpose</h4>We aimed to describe the weight-for-age Z-score growth trajectory (WAZ-GT) of infants with complex congenital heart disease (cCHD) after neonatal cardiac surgery in the first 4 months of life and assess potential risk factors.<h4>Methods</h4>We utilized data from a previously reported trial of the REACH telehealth home monitoring (NCT01941667) program which evaluated 178 infants with cCHD from 2012 to 2017. Over the first 4 months of life, weekly infant weights were converted to ...[more]

PMID: 35598589

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Dataset Information

New insights on growth trajectory in infants with complex congenital heart disease.

Purpose

Methods

Results

Conclusions

Practice implications

Publications

New insights on growth trajectory in infants with complex congenital heart disease.

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