Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC.
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ABSTRACT:
SUBMITTER: Meurer SK
PROVIDER: S-EPMC9447916 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC.
Meurer Steffen K SK Brenner David A DA Weiskirchen Ralf R
PloS one 20220906 9
Misidentification, cross-contamination and genetic drift of continuous animal cell lines are persistent problems in biomedical research, leading to erroneous results and inconsistent or invalidated studies. The establishment of immortalized hepatic stellate cell line Col-GFP HSC was reported in PLoS One in the year 2013. In the present study a multi loci short tandem repeat signature for this cell line was established that allows for unique cell line authentication. ...[more]
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