Dataset Information
Cleft lip and palate: series of unusual clinical cases.
Ontology highlight
ABSTRACT: Unlabelled
Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face, corresponding to approximately 65% of all malformations of the craniofacial region.Aim
to describe unusual clinical cases of non-syndromic CL/P (CL/PNS), diagnosed in a reference service in Minas Gerais, Brazil, and correlate these alterations with possible risk factors.Materials and methods
we carried out a retrospective study, between the years of 1992 and the 1st half of 2009, from medical records.Results
Among the 778 cases of CL/PNS diagnosed in the period of 17 years, 5 (0.64%) were unusual CL/PNS, and all patients were male. It was found that among the 5 patients, 2 had incomplete right cleft lip with incomplete cleft palate, 2 were affected by left incomplete cleft lip and incomplete cleft palate, and 1 had a cleft lip and palate associated with complete right cleft palate. Risk factors such as consanguinity, maternal smoking and alcohol consumption, medication usage during pregnancy, history of abortion and/or stillbirths and maternal diseases were not associated with unusual CL/PNS.Conclusions
This study described 5 unusual cases of CL/PNS in a Brazilian population; no associations with the risk factors analyzed were seen. It also confirmed the unusualness of the prevalence of such alterations.
SUBMITTER: Paranaiba LM
PROVIDER: S-EPMC9450715 | biostudies-literature | 2010 Sep-Oct
REPOSITORIES: biostudies-literature
Publications
Cleft lip and palate: series of unusual clinical cases.
Brazilian journal of otorhinolaryngology 20100901 5
<h4>Unlabelled</h4>Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face, corresponding to approximately 65% of all malformations of the craniofacial region.<h4>Aim</h4>to describe unusual clinical cases of non-syndromic CL/P (CL/PNS), diagnosed in a reference service in Minas Gerais, Brazil, and correlate these alterations with possible risk factors.<h4>Materials and methods</h4>we carried out a retrospective study, between the years of 1992 and the 1st half ...[more]