Ontology highlight
ABSTRACT:
SUBMITTER: Repetto O
PROVIDER: S-EPMC9456176 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Repetto Ombretta O Caggiari Laura L De Zorzi Mariangela M Elia Caterina C Mussolin Lara L Buffardi Salvatore S Pillon Marta M Muggeo Paola P Casini Tommaso T Steffan Agostino A Mauz-Körholz Christine C Mascarin Maurizio M De Re Valli V
International journal of molecular sciences 20220831 17
Classical pediatric Hodgkin Lymphoma (HL) is a rare malignancy. Therapeutic regimens for its management may be optimized by establishing treatment response early on. The aim of this study was to identify plasma protein biomarkers enabling the prediction of relapse in pediatric/adolescent HL patients treated under the pediatric EuroNet-PHL-C2 trial. We used untargeted liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomics at the time of diagnosis—before any therapy—as semiquan ...[more]