Dataset Information

Exercise-induced hypoalgesia (EIH) in response to different exercise intensities.

ABSTRACT:

Purpose

Acute physical activity leads to exercise-induced hypoalgesia (EIH). The aim of this study was to investigate the effects of four different exercise intensities on EIH.

Methods

25 male (age: 24.7 ± 3.0) subjects underwent four different exercise sessions on a bicycle ergometer for 30 min each at 60, 80, 100, and 110% of the individual anaerobic threshold on separate days in a randomized crossover design. Before, as well as 5- and 45-min post-exercise, pain sensitivity was measured employing pain pressure thresholds (PPT) at the elbow, knee, and ankle joints as well as the sternum and forehead. Besides, conditioned pain modulation (CPM) was conducted using thermal test- and conditioned stimuli before, 5-, and 45-min post-exercise.

Results

A main time effect was observed regarding PPT at all landmarks except for the forehead with higher values observed 5 and 45 min post-exercise compared to the pre-values. Yet, no interaction effects occurred. CPM did not change in response to any of the intensities used.

Conclusion

EIH occurs 5 and 45 min after exercise regardless of the intensity used at the joints and sternum which might be explained by local pain-inhibiting pathways and probably to a limited degree by central mechanisms, as no hypoalgesia was observed at the forehead and no changes in CPM occurred.

SUBMITTER: Tomschi F

PROVIDER: S-EPMC9463310 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Publications

Exercise-induced hypoalgesia (EIH) in response to different exercise intensities.

Tomschi Fabian F Lieverkus Dennis D Hilberg Thomas T

European journal of applied physiology 20220709 10

<h4>Purpose</h4>Acute physical activity leads to exercise-induced hypoalgesia (EIH). The aim of this study was to investigate the effects of four different exercise intensities on EIH.<h4>Methods</h4>25 male (age: 24.7 ± 3.0) subjects underwent four different exercise sessions on a bicycle ergometer for 30 min each at 60, 80, 100, and 110% of the individual anaerobic threshold on separate days in a randomized crossover design. Before, as well as 5- and 45-min post-exercise, pain sensitivity was ...[more]

PMID: 35809091

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Project description:BackgroundAcute physical activity often induces an acute reduction in pain sensitivity known as exercise induced hypoalgesia (EIH). The aim of this study was to investigate the effects of a high intensity functional training (HIFT) on EIH compared to a control session.Methods50 (age: 26.0 ± 2.7; 23 female) participants successfully conducted this study consisting of a pre-experimental test as well as a 12-minute HIFT (body-weight exercises) and a 12-minute control (supervised breathing) session in a randomized crossover design. Pre and post, pressure pain thresholds (PPT) were measured at the ankles, knees, elbows, and forehead.ResultsThe HIFT resulted in a relative maximum and average heart rate of 96.2% (± 3.6%) and 91.1% (± 4.2%), respectively, and maximum and average RPE values of 19.1 (± 1.2) and 16.2 (± 1.4), respectively. Results reveal a significant 'Intervention' × 'Time point' interaction (p < 0.001) for PPT (pooled for one average value) with hypoalgesia observed following the HIFT (p < 0.001; pre: 56.0 ± 16.8, post: 61.6 ± 19.0 [Newton]) and no change following the control (p = 0.067; pre: 56.6 ± 18.4, post: 55.3 ± 18.9 [Newton]). Further, a significant 'Time' × 'Intervention' × 'Landmark' interaction effect (p = 0.024) is observed and all landmarks showed significant hypoalgesia following HIFT (p < 0.01), except for the right elbow and forehead. Following control, no hypoalgesia was observed at any landmark. Analysing male and female participants separately, it was observed that EIH occured only in men.ConclusionA HIFT using bodyweight exercises reduces pain sensitivity. Hence, combining strength and aerobically demanding exercises in a short but high intensity manner, as done in HIFT, can be seen as a usable tool to induce hypoalgesia. Yet, these results were observed only in male participants, necessitating future sex-specific research.Trial registrationDRKS00034391, retrospectively registered on the 4th of June 2024.

Project description:Fruit color is an important economic character of blueberry, determined by the amount of anthocyanin content. Anthocyanin synthesis within the blueberry fruits is significantly affected by light. To reveal the physiological response mechanism of anthocyanin synthesis in blueberry fruits in different light intensities, four light intensities (100% (CK), 75%, 50% and 25%) were set for the 'O'Neal' southern highbush blueberry as the experimental material in our study. The relationship between endogenous hormones content, associated enzyme activities, and variations with the anthocyanin content in blueberry fruits under various light intensities during the white fruit stage (S1), purple fruit stage (S2), and blue fruit stage (S3) were studied. The results showed that adequate light could significantly promote anthocyanin synthesis in blueberry fruits (P < 0.05). Blueberry fruits had an anthocyanin content that was 1.76~24.13 times higher under 100% light intensity than it was under non-full light intensity. Different light intensities significantly affected the content of endogenous hormones and the activity of associated enzymes in anthocyanin synthesis pathway (P < 0.05). Among them, the JA (jasmonic acid) content and PAL (phenylalanine ammonia lyase) activity of fruits under 100% light intensity were 2.49%~41.83% and 2.47%~48.48% higher than those under other light intensity, respectively. And a significant correlation was found between the variations in anthocyanin content in fruits and the content or activities of JA, ABA (abscisic acid), ETH (ethylene), GA3 (gibberellin 3), IAA (indoleacetic acid), PAL, CHI (chalcone isomerase), DFR (dihydroflavonol reductase) and UFGT (UDP-glucose: flavonoid 3-glucosyltransferase) (P < 0.05). It indicated that 100% light intensity significantly promoted anthocyanin synthesis in blueberry fruits by affecting endogenous hormones content and associated enzyme activities in the anthocyanin synthesis pathway. This study will lay a foundation for further research on the molecular mechanism of light intensity regulating anthocyanin synthesis in blueberry.

Dataset Information

Exercise-induced hypoalgesia (EIH) in response to different exercise intensities.

Purpose

Methods

Results

Conclusion

Publications

Exercise-induced hypoalgesia (EIH) in response to different exercise intensities.

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