Ontology highlight
ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC9465335 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Yang Yiran Y Wang Wanning W Weng Jing J Li Huifang H Ma Yanmin Y Liu Lingyan L Ma Wei W
Frontiers in immunology 20220829
The HLA class Ib molecule is an alloantigen that causes transplant rejection on behalf of individual human and plays an important role in maternal-fetal immune tolerance. Early studies on HLA class Ib focused on the mechanism of HLA-G-induced immune escape, but in recent years, studies on the mechanism of HLA-G have deepened and gradually explored the mechanism of HLA-E and HLA-F, which are also HLA class Ib molecules. In the maternal-fetal interface, trophoblast cells express HLA class Ib molec ...[more]