Individual copy number variation and extensive diversity between major MHC-DAB1 allelic lineages in the European bitterling.
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ABSTRACT:
SUBMITTER: Talarico L
PROVIDER: S-EPMC9467946 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
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Individual copy number variation and extensive diversity between major MHC-DAB1 allelic lineages in the European bitterling.
Talarico Lorenzo L Bryjová Anna A Čížková Dagmar D Douda Karel K Reichard Martin M
Immunogenetics 20220111 5
Polymorphism of the major histocompatibility complex (MHC), DAB1 gene was characterized for the first time in the European bitterling (Rhodeus amarus), a freshwater fish employed in studies of host-parasite coevolution and mate choice, taking advantage of newly designed primers coupled with high-throughput amplicon sequencing. Across 221 genotyped individuals, we detected 1-4 variants per fish, with 28% individuals possessing 3-4 variants. We identified 36 DAB1 variants, and they showed high seq ...[more]
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