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ABSTRACT:
SUBMITTER: Bates S
PROVIDER: S-EPMC9470385 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Bates Stephen S Tibshirani Robert R
Biometrics 20190329 2
Positive-valued signal data is common in the biological and medical sciences, due to the prevalence of mass spectrometry other imaging techniques. With such data, only the relative intensities of the raw measurements are meaningful. It is desirable to consider models consisting of the log-ratios of all pairs of the raw features, since log-ratios are the simplest meaningful derived features. In this case, however, the dimensionality of the predictor space becomes large, and computationally effici ...[more]