Ontology highlight
ABSTRACT: Design
Single-center, observational study.Setting
Medical ICU at an academic medical center.Patients
Critically ill adults receiving mechanical ventilation from July 2018 to February 2021, excluding patients with COVID-19, with race documented as Black or White in the electronic medical record, who had a pair of Spo2 and Sao2 measurements collected within 10 minutes of each other.Interventions
None.Measurements
We included 1,024 patients with 5,557 paired measurements within 10 minutes, of which 3,885 (70%) were within 1 minute. Of all pairs, 769 (14%) were from Black patients and 4,788 (86%) were from White patients. In analyses using a mixed-effects model, we found that across the range of Spo2 values of 92-98%, the associated Sao2 value was approximately 1% point lower for Black patients compared with White patients. Among patients with a Spo2 value between 92% and 96%, Black patients were more likely to have both hypoxemia (3.5% vs 1.1%; p = 0.002) and hyperoxemia (4.7% vs 2.4%; p = 0.03), compared with White patients.Conclusions
Among patients with a measured Spo2 of 92-96%, greater variation in Sao2 values at a given Spo2 resulted in a higher occurence rate of both hypoxemia and hyperoxemia for Black patients compared with White patients.
SUBMITTER: Seitz KP
PROVIDER: S-EPMC9478292 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Critical care explorations 20220914 9
For critically ill adults, oxygen saturation is continuously monitored using pulse oximetry (Spo<sub>2</sub>) as a surrogate for arterial oxygen saturation (Sao<sub>2</sub>). Skin pigmentation may affect accuracy of Spo<sub>2</sub> by introducing error from statistical bias, variance, or both. We evaluated relationships between race, Spo<sub>2</sub>, Sao<sub>2</sub>, and hypoxemia (Sao<sub>2</sub> < 88%) or hyperoxemia (Pao<sub>2</sub> > 150 mm Hg) among adults receiving mechanical ventilation i ...[more]