Ontology highlight
ABSTRACT:
SUBMITTER: Liu M
PROVIDER: S-EPMC94800 | biostudies-literature | 2000 Nov
REPOSITORIES: biostudies-literature
Liu M M Turner R J RJ Winstone T L TL Saetre A A Dyllick-Brenzinger M M Jickling G G Tari L W LW Weiner J H JH Taylor D E DE
Journal of bacteriology 20001101 22
The Escherichia coli chromosomal determinant for tellurite resistance consists of two genes (tehA and tehB) which, when expressed on a multicopy plasmid, confer resistance to K(2)TeO(3) at 128 microg/ml, compared to the MIC of 2 microg/ml for the wild type. TehB is a cytoplasmic protein which possesses three conserved motifs (I, II, and III) found in S-adenosyl-L-methionine (SAM)-dependent non-nucleic acid methyltransferases. Replacement of the conserved aspartate residue in motif I by asparagin ...[more]