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VibD and VibH are required for late steps in vibriobactin biosynthesis in Vibrio cholerae.


ABSTRACT: Vibrio cholerae synthesizes the catechol siderophore vibriobactin. In this report, we present the complete map of a vibriobactin gene region containing two previously unreported vibriobactin biosynthetic genes. vibD encodes a phosphopantetheinyl transferase, and vibH encodes a novel nonribosomal peptide synthase. Both VibD and VibH are required for vibriobactin biosynthesis.

SUBMITTER: Wyckoff EE 

PROVIDER: S-EPMC95076 | biostudies-literature | 2001 Mar

REPOSITORIES: biostudies-literature

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VibD and VibH are required for late steps in vibriobactin biosynthesis in Vibrio cholerae.

Wyckoff E E EE   Smith S L SL   Payne S M SM  

Journal of bacteriology 20010301 5


Vibrio cholerae synthesizes the catechol siderophore vibriobactin. In this report, we present the complete map of a vibriobactin gene region containing two previously unreported vibriobactin biosynthetic genes. vibD encodes a phosphopantetheinyl transferase, and vibH encodes a novel nonribosomal peptide synthase. Both VibD and VibH are required for vibriobactin biosynthesis. ...[more]

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