Ontology highlight
ABSTRACT:
SUBMITTER: Rogier E
PROVIDER: S-EPMC9514350 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Rogier Eric E McCaffery Jessica N JN Mohamed Mohamed Ali MA Herman Camelia C Nace Doug D Daniels Rachel R Lucchi Naomi N Jones Sophie S Goldman Ira I Aidoo Michael M Cheng Qin Q Kemenang Edie A EA Udhayakumar Venkatachalam V Cunningham Jane J
Emerging infectious diseases 20221001 10
Deletions of pfhrp2 and paralogue pfhrp3 (pfhrp2/3) genes threaten Plasmodium falciparum diagnosis by rapid diagnostic test. We examined 1,002 samples from suspected malaria patients in Djibouti City, Djibouti, to investigate pfhrp2/3 deletions. We performed assays for Plasmodium antigen carriage, pfhrp2/3 genotyping, and sequencing for 7 neutral microsatellites to assess relatedness. By PCR assay, 311 (31.0%) samples tested positive for P. falciparum infection, and 296 (95.2%) were successfully ...[more]