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ABSTRACT:
SUBMITTER: Hamaguchi M
PROVIDER: S-EPMC9519412 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Hamaguchi Masahide M Yoshimura Yuta Y Nakajima Hanako H Tanaka Toru T Hasegawa Goji G Ishii Michiyo M Okada Hiroshi H Mitsuhashi Kazuteru K Kitagawa Noriyuki N Okamura Takuro T Hashimoto Yoshitaka Y Majima Saori S Senmaru Takafumi T Ushigome Emi E Nakanishi Naoko N Asano Mai M Yamazaki Masahiro M Fukui Michiaki M
Journal of clinical biochemistry and nutrition 20220517 2
To clarify the frequency of hypoglycemia in patients with type 1 diabetes mellitus receiving dapagliflozin combination therapy to reduce their basal insulin dose. Sixty subjects were assigned to two groups according to their basal insulin-to-total daily dose (TDD) ratio: group A (basal insulin/TDD <40%) and group B (≥40%). Reduction of the basal insulin dose was instituted in group B, but not in group A. The number of hypoglycemic events per day and ketosis frequency were the primary and seconda ...[more]