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Orientation pinwheels in primary visual cortex of a highly visual marsupial.

ABSTRACT: Primary visual cortices in many mammalian species exhibit modular and periodic orientation preference maps arranged in pinwheel-like layouts. The role of inherited traits as opposed to environmental influences in determining this organization remains unclear. Here, we characterize the cortical organization of an Australian marsupial, revealing pinwheel organization resembling that of eutherian carnivores and primates but distinctly different from the simpler salt-and-pepper arrangement of eutherian rodents and rabbits. The divergence of marsupials from eutherians 160 million years ago and the later emergence of rodents and rabbits suggest that the salt-and-pepper structure is not the primitive ancestral form. Rather, the genetic code that enables complex pinwheel formation is likely widespread, perhaps extending back to the common therian ancestors of modern mammals.

SUBMITTER: Jung YJ

PROVIDER: S-EPMC9524828 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Orientation pinwheels in primary visual cortex of a highly visual marsupial.

Jung Young Jun YJ Almasi Ali A Sun Shi H SH Yunzab Molis M Cloherty Shaun L SL Bauquier Sebastien H SH Renfree Marilyn M Meffin Hamish H Ibbotson Michael R MR

Science advances 20220930 39

Primary visual cortices in many mammalian species exhibit modular and periodic orientation preference maps arranged in pinwheel-like layouts. The role of inherited traits as opposed to environmental influences in determining this organization remains unclear. Here, we characterize the cortical organization of an Australian marsupial, revealing pinwheel organization resembling that of eutherian carnivores and primates but distinctly different from the simpler salt-and-pepper arrangement of euther ...[more]

PMID: 36179020

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