Unknown

Dataset Information

0

The role of macrophage subtypes and exosomes in immunomodulation.


ABSTRACT: Macrophages are influential members of the innate immune system that can be reversibly polarized by different microenvironment signals. Cell polarization leads to a wide range of features, involving the migration, development, and organization of the cells. There is mounting evidence that macrophage polarization plays a key role in the initiation and development of a wide range of diseases. This study aims to give an overview of macrophage polarization, their different subtypes, and the importance of alternatively activated M2 macrophage and classically activated M1 macrophage in immune responses and pathological conditions. This review provides insight on the role of exosomes in M1/M2-like macrophage polarization and their potential as a promising therapeutic candidate.

SUBMITTER: Gharavi AT 

PROVIDER: S-EPMC9528143 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

altmetric image

Publications

The role of macrophage subtypes and exosomes in immunomodulation.

Gharavi Abdulwahab Teflischi AT   Hanjani Niloofar Asadi NA   Movahed Elaheh E   Doroudian Mohammad M  

Cellular & molecular biology letters 20221003 1


Macrophages are influential members of the innate immune system that can be reversibly polarized by different microenvironment signals. Cell polarization leads to a wide range of features, involving the migration, development, and organization of the cells. There is mounting evidence that macrophage polarization plays a key role in the initiation and development of a wide range of diseases. This study aims to give an overview of macrophage polarization, their different subtypes, and the importan  ...[more]

Similar Datasets

| S-EPMC4102923 | biostudies-literature
| S-EPMC8128914 | biostudies-literature
| S-EPMC10666760 | biostudies-literature
| S-EPMC6682414 | biostudies-literature
| S-EPMC6392032 | biostudies-literature
| S-EPMC6386606 | biostudies-literature
| S-EPMC8343919 | biostudies-literature
| S-EPMC6522546 | biostudies-literature
| S-EPMC4724110 | biostudies-literature
| S-EPMC10886698 | biostudies-literature