Ontology highlight
ABSTRACT:
SUBMITTER: Ullrich S
PROVIDER: S-EPMC9538446 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Ullrich Sven S Nitsche Christoph C
Chembiochem : a European journal of chemical biology 20220908 19
Emerging variants of SARS-CoV-2 and potential novel epidemic coronaviruses underline the importance of investigating various viral proteins as potential drug targets. The papain-like protease of coronaviruses has been less explored than other viral proteins; however, its substantive role in viral replication and impact on the host immune response make it a suitable target to study. This review article focuses on the structure and function of the papain-like protease (PL<sup>pro</sup> ) of SARS-C ...[more]